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KMID : 0351619760170020215
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Kyungpook Medical Journal
1976 Volume.17 No. 2 p.215 ~ p.218
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Treatment of Ehrlich Careinoma(Solid Tumor) with Tubercin-3 and 5--Fluorouracil
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全石吉/Zeon, Seock-Kil
羅雨淵/鄭泰浩/Ra, Woo Youn/Chung, Tai Ho
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Abstract
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Chung had extracted Tubercin-3, from tubercle bacilli and applied to various types of caner with clinical improement(1974). On this study to determine the effect of Tubercin-3 and 5-Fluorouracil in the the Ehrlich ascites carcinoma, 48 mice were divided into 6 groups of 8 animals receiving BCG, Tubercin-3, 5-Fluorouracil, BCG and 5-Fluorouracil, Tubercin-3 and 5-Fluorouracil, and control for 10 days.
On the 14th days after cancer cell inoculation, all surviving mice were carefvlly taken out and weighed. The average weight of solid tumor was calculated i each group and results were shown below:
Nontreated(control); 3.52 gm, BCG treated; 3.46gm, Tubercin-3 treated; 3.03gm, 5-Flurouracil treated; 3.12gm, BCG and 5-Fluorouracil treated; 4.02gm, Tubercin-and 5-Fluorouracil treated;1.75gm.
Combined treatment of Tubercin-3 and 5-fluorouracil seemed to be effective in the solid type of Ehrlich ascites carcinoma.
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